MZ-1
Product Specifications
CAS Number
1797406-69-9
Target
Epigenetic Reader Domain
Applications
Epigenetics
Smiles
CC1=C (SC2=C1C (=NC (C3=NN=C (N32) C) CC (=O) NCCOCCOCCOCC (=O) NC (C (=O) N4CC (CC4C (=O) NCC5=CC=C (C=C5) C6=C (N=CS6) C) O) C (C) (C) C) C7=CC=C (C=C7) Cl) C
Molecular Formula
C49H60ClN9O8S2
Additionnal Information
MZ-1 is a PROTAC degrader of bromodomain-containing protein 4 (BRD4) . MZ-1 binds to the Brd bromodomain with Kd of 62 nM, 60 nM, 21 nM, 13 nM, 39 nM and 15 nM for Brd2BD1, Brd2BD2, Brd3BD1, Brd3BD2, Brd4BD1 and Brd4BD2.
Storage Conditions
3 years -20°C powder
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