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MZ-1

Product Specifications

CAS Number

1797406-69-9

Target

Epigenetic Reader Domain

Applications

Epigenetics

Smiles

CC1=C (SC2=C1C (=NC (C3=NN=C (N32) C) CC (=O) NCCOCCOCCOCC (=O) NC (C (=O) N4CC (CC4C (=O) NCC5=CC=C (C=C5) C6=C (N=CS6) C) O) C (C) (C) C) C7=CC=C (C=C7) Cl) C

Molecular Formula

C49H60ClN9O8S2

Additionnal Information

MZ-1 is a PROTAC degrader of bromodomain-containing protein 4 (BRD4) . MZ-1 binds to the Brd bromodomain with Kd of 62 nM, 60 nM, 21 nM, 13 nM, 39 nM and 15 nM for Brd2BD1, Brd2BD2, Brd3BD1, Brd3BD2, Brd4BD1 and Brd4BD2.

Storage Conditions

3 years -20°C powder

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