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UT-34

Product Specifications

CAS Number

2168525-92-4

Target

Androgen Receptor

Applications

Endocrinology & Hormones

Smiles

CC (CN1C=C (C=N1) F) (C (=O) NC2=CC (=C (C=C2) C#N) C (F) (F) F) O

Molecular Formula

C15H12F4N4O2

Additionnal Information

UT-34 is a potent, selective and orally bioavailable second-generation androgen receptor (AR) pan antagonist and degrader with IC50 of 203.46 nM, 80.78 nM and 94.17 nM for wild-type, T877A and W741L AR, respectively. UT-34 is a potential next-generation therapeutic for -resistant prostate cancer.

Storage Conditions

3 years -20°C powder

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