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LLY-283

Product Specifications

CAS Number

2040291-27-6

Target

PRMT

Applications

Epigenetics

Smiles

C1=CC=C (C=C1) C (C2C (C (C (O2) N3C=CC4=C (N=CN=C43) N) O) O) O

Molecular Formula

C17H18N4O4

Additionnal Information

LLY-283 is a novel and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) . LLY-283 inhibits PRMT5 enzymatic activity in vitro and in cells with IC50 of 22 nM and 25 nM, respectively. LLY-283 shows antitumor activity.

Storage Conditions

3 years -20°C powder

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