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YKL-5-124

Product Specifications

CAS Number

1957203-01-8

Target

CDK

Applications

Cell Cycle

Smiles

CC1 (C2=C (CN1C (=O) NC (CN (C) C) C3=CC=CC=C3) C (=NN2) NC (=O) C4=CC=C (C=C4) NC (=O) C=C) C

Molecular Formula

C28H33N7O3

Additionnal Information

YKL-5-124 is a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for inhibiting CDK7/Mat1/CycH, CDK2 and CDK9 respectively. It displays biochemical and cellular selectivity for CDK7 over CDK12/13.

Storage Conditions

3 years -20°C powder

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