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PDD00017273

Product Specifications

CAS Number

1945950-21-9

Target

PARG

Applications

Metabolism

Smiles

CC1=NN (C (=C1) CN2C3=C (C=C (C=C3) S (=O) (=O) NC4 (CC4) C) C (=O) N (C2=O) CC5=CN=C (S5) C) C

Molecular Formula

C23H26N6O4S2

Additionnal Information

PDD00017273 is a potent and selective poly (ADP ribose) glycohydrolase (PARG) inhibitor with an IC50 of 26 nM. PDD00017273 exhibits >350-fold selectivity for PARG over a panel of ion channels, enzymes and receptors, including PARP1 and ARH3.

Storage Conditions

3 years -20°C powder

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