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Pyrotinib dimaleate

Product Specifications

CAS Number

1397922-61-0

Synonyms

SHR-1258, BLTN, Pyrroltinib dimaleate

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

CCOC1=C (C=C2C (=C1) N=CC (=C2NC3=CC (=C (C=C3) OCC4=CC=CC=N4) Cl) C#N) NC (=O) C=CC5CCCN5C

Molecular Formula

C40H39ClN6O11

Additionnal Information

Pyrotinib dimaleate is a potent and selective irreversible dual tyrosine kinase inhibitor of EGFR and HER2 with IC50 of 0.013 μM and 0.038 μM, respectively.

Storage Conditions

3 years -20°C powder

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