TAS4464

Product Specifications

CAS Number

1848959-10-3

Target

E1 Activating

Applications

Ubiquitin

Smiles

CCOC1=CC=CC (=C1C#CC2=C[N] (C3OC (CN[S] (N) (=O) =O) C (O) C3O) C4=C2C (=NC=N4) N) F

Molecular Formula

C21H23FN6O6S

Additionnal Information

TAS4464 is a potent and highly selective NEDD8 activating enzyme (NAE) inhibitor with IC50 of 0.955 nM. TAS4464 exhibits superior antitumor activity with prolonged target inhibition.

Storage Conditions

3 years -20°C powder

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