TAS4464
Product Specifications
CAS Number
1848959-10-3
Target
E1 Activating
Applications
Ubiquitin
Smiles
CCOC1=CC=CC (=C1C#CC2=C[N] (C3OC (CN[S] (N) (=O) =O) C (O) C3O) C4=C2C (=NC=N4) N) F
Molecular Formula
C21H23FN6O6S
Additionnal Information
TAS4464 is a potent and highly selective NEDD8 activating enzyme (NAE) inhibitor with IC50 of 0.955 nM. TAS4464 exhibits superior antitumor activity with prolonged target inhibition.
Storage Conditions
3 years -20°C powder
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ID3 (1R21, BHLHB25, HEIR1, DNA-binding Protein Inhibitor ID-3, Class B Basic Helix-loop-helix Protein 25, Helix-loop-helix Protein HEIR-1, ID-like Protein Inhibitor HLH 1R21, Inhibitor of DNA Binding 3) (MaxLight 405)
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