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GSK3179106

Product Specifications

CAS Number

1627856-64-7

Target

C-RET

Applications

Protein Tyrosine Kinase

Smiles

CCOC1=CC (=O) NC=C1C2=CC (=C (C=C2) CC (=O) NC3=NOC (=C3) C (C) (C) C (F) (F) F) F

Molecular Formula

C22H21F4N3O4

Additionnal Information

GSK3179106 is a potent, selective, and gut-restricted pyridone hinge binder small molecule RET (c-RET) kinase inhibitor with a RET IC50 of 0.3 nM and is efficacious in vivo.

Storage Conditions

3 years -20°C powder

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