Zipalertinib (TAS6417)
Product Specifications
CAS Number
1661854-97-2
Synonyms
CLN-081, TPC-064
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1=CC (CN2C1=C (C3=C (N=CN=C32) N) C4=CC5=CC=CC=C5N=C4) NC (=O) C=C
Molecular Formula
C23H20N6O
Additionnal Information
Zipalertinib (TAS6417) is a novel EGFR inhibitor that targets EGFR exon 20 insertion mutations while sparing wild-type (WT) EGFR. IC50 values ranges from 1.1 ± 0.1 to 8.0 ± 1.1 nmol/L.
Storage Conditions
3 years -20°C powder
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