Brepocitinib (PF-06700841)
Product Specifications
CAS Number
1883299-62-4
Synonyms
PF-841
Target
JAK
Applications
Angiogenesis
Smiles
CN1C=C (C=N1) NC2=NC=CC (=N2) N3CC4CCC (C3) N4C (=O) C5CC5 (F) F
Molecular Formula
C18H21F2N7O
Additionnal Information
Brepocitinib (PF-06700841, PF-841) is a potent inhibitor of Tyk2 and Jak1 with IC50s of 23 nM, 17 nM, 77 nM for Tyk2, Jak1 and Jak2 respectively. It has appropriate in-family selectivity against JAK2 and JAK3.
Storage Conditions
3 years -20°C powder
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