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Uzansertib (INCB053914)

Product Specifications

CAS Number

2088852-47-3

Target

Pim

Applications

JAK/STAT

Smiles

CC1CN (CC (C1O) N) C2=C3CCC (C3=NC=C2NC (=O) C4=NC (=C (C=C4) F) C5=C (C=CC=C5F) F) O.OP (=O) (O) O

Molecular Formula

C26H26F3N5O3.H3O4P

Additionnal Information

Uzansertib (INCB053914) is a novel, ATP-competitive, small molecule, pan-inhibitor of PIM kinases with IC50 values of 0.24 nM, 30 nM and 0.12 nM for PIM1, PIM2 and PIM3 respectively in biochemical assays.

Storage Conditions

3 years -20°C powder

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