A1874
Product Specifications
CAS Number
2064292-12-0
Target
Epigenetic Reader Domain
Applications
Epigenetics
Smiles
CC1=C (SC2=C1C (=NC (C3=NN=C (N32) C) CC (=O) NCCOCCOCCOCCNC (=O) C4=CC (=C (C=C4) NC (=O) C5C (C (C (N5) CC (C) (C) C) (C#N) C6=C (C=C (C=C6) Cl) F) C7=C (C (=CC=C7) Cl) F) OC) C8=CC=C (C=C8) Cl) C
Molecular Formula
C58H62Cl3F2N9O7S
Additionnal Information
A1874 is a much improved nutlin-based, BRD4-degrading PROTAC and is able to degrade its target protein by 98% with nanomolar potency.
Storage Conditions
3 years -20°C powder
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