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LY 3200882

Product Specifications

CAS Number

1898283-02-7

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

CC (C) (C1=NC=CC (=C1) NC2=NC=CC (=C2) OC3=CN (N=C3C4CCOCC4) C5CC5) O

Molecular Formula

C24H29N5O3

Additionnal Information

LY 3200882 is a potent, highly selective inhibitor of TGF-β receptor type 1 (TGFβRI) . It potently inhibits TGFβ mediated SMAD phosphorylation in vitro in tumor and immune cells and in vivo in subcutaneous tumors in a dose dependent fashion.

Storage Conditions

3 years -20°C powder

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