IDF-11774

Product Specifications

CAS Number

1429054-28-3

Target

HIF

Applications

Angiogenesis

Smiles

CN1CCN (CC1) C (=O) COC2=CC=C (C=C2) C34CC5CC (C3) CC (C5) C4

Molecular Formula

C23H32N2O2

Additionnal Information

IDF-11774 is a hypoxia-inducible factor-1 (HIF-1) inhibitor. It reduces the HRE-luciferase activity of HIF-1α (IC50 = 3.65 μM) and blocks HIF-1α accumulation under hypoxia in HCT116 human colon cancer cells.

Storage Conditions

3 years -20°C powder

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