Adavivint (SM04690)
Product Specifications
CAS Number
1467093-03-3
Synonyms
Lorecivivint
Target
Wnt/beta-catenin
Applications
Cytoskeletal Signaling
Smiles
CC (C) CC (=O) NC1=CN=CC (=C1) C2=CC3=C (C=C2) NN=C3C4=NC5=C (N4) C=NC=C5C6=CC (=CC=C6) F
Molecular Formula
C29H24FN7O
Additionnal Information
Adavivint (SM04690, Lorecivivint) is a potent and specific inhibitor of canonical Wnt signaling with an EC50 of 19.5 nM for inhibiting the TCF/LEF reporter. It is ∼150- to 500-fold more potent than the other known Wnt inhibitors across multiple cellular assays.
Storage Conditions
3 years -20°C powder
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