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Naporafenib (LXH254)

Product Specifications

CAS Number

1800398-38-2

Target

Raf

Applications

MAPK

Smiles

CC1=C (C=C (C=C1) NC (=O) C2=CC (=NC=C2) C (F) (F) F) C3=CC (=NC (=C3) OCCO) N4CCOCC4

Molecular Formula

C25H25F3N4O4

Additionnal Information

Naporafenib (LXH254) is a type II ATP-competitive inhibitor that inhibits both B- and CRAF kinase activities at picomolar concentrations with a high degree of selectivity against a panel of 456 human kinases and in cell-based assays.

Storage Conditions

3 years -20°C powder

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