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A-485

Product Specifications

CAS Number

1889279-16-6

Target

Histone Acetyltransferase

Applications

Epigenetics

Smiles

CC (C (F) (F) F) N (CC1=CC=C (C=C1) F) C (=O) CN2C (=O) C3 (CCC4=C3C=CC (=C4) NC (=O) NC) OC2=O

Molecular Formula

C25H24F4N4O5

Additionnal Information

A-485 is a potent, selective and drug-like p300/CBP catalytic inhibitor with an IC50 of 0.06 μM for p300 HAT. It is selective over BET bromodomain proteins and >150 non-epigenetic targets.

Storage Conditions

3 years -20°C powder

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