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Verinurad (RDEA3170)

Product Specifications

CAS Number

1352792-74-5

Target

OAT

Applications

Transmembrane Transporters

Smiles

CC (C) (C (=O) O) SC1=C (C=NC=C1) C2=CC=C (C3=CC=CC=C32) C#N

Molecular Formula

C20H16N2O2S

Additionnal Information

Verinurad (RDEA3170) is a high-affinity inhibitor of the URAT1 transporter with an IC50 of 25 nM for inhibiting transport activity of human URAT1. It inhibits the related URAT1 homologs OAT4 and OAT1 with approximately 200-fold lower affinity compared to URAT1 with IC50 values of 5.9 μM and 4.6 μM, respectively.

Storage Conditions

3 years -20°C powder

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