Verinurad (RDEA3170)
Product Specifications
CAS Number
1352792-74-5
Target
OAT
Applications
Transmembrane Transporters
Smiles
CC (C) (C (=O) O) SC1=C (C=NC=C1) C2=CC=C (C3=CC=CC=C32) C#N
Molecular Formula
C20H16N2O2S
Additionnal Information
Verinurad (RDEA3170) is a high-affinity inhibitor of the URAT1 transporter with an IC50 of 25 nM for inhibiting transport activity of human URAT1. It inhibits the related URAT1 homologs OAT4 and OAT1 with approximately 200-fold lower affinity compared to URAT1 with IC50 values of 5.9 μM and 4.6 μM, respectively.
Storage Conditions
3 years -20°C powder
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