What is the catalog number for Enitociclib (BAY 1251152)?

The catalog number for Enitociclib (BAY 1251152) is S8730-10mM/1mL.

What sizes are available for Enitociclib (BAY 1251152)?

Enitociclib (BAY 1251152) is available in the following size(s): 10 mM/1mL.

Is Enitociclib (BAY 1251152) in stock?

Enitociclib (BAY 1251152) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Enitociclib (BAY 1251152)?

Enitociclib (BAY 1251152) is manufactured by Bimake.

What is the estimated delivery time for Enitociclib (BAY 1251152)?

Estimated delivery time for Enitociclib (BAY 1251152) is approximately 15 business day(s), depending on your location.

Enitociclib (BAY 1251152)

Product Specifications

CAS Number

1610358-56-9

Synonyms

(+) -BAY-1251152

Target

CDK

Applications

Cell Cycle

Smiles

COC1=C (C=CC (=C1) F) C2=CC (=NC=C2F) NC3=NC=CC (=C3) CS (=N) (=O) C

Molecular Formula

C19H18F2N4O2S

Additionnal Information

Enitociclib (BAY 1251152) is a potent PTEFb/CDK9 inhibitor with an IC50 value of 3 nM for CDK9 and an at least 50-fold selectivity against other CDKs in enzymatic assays. BAY1251152 binds to and blocks the phosphorylation and kinase activity of CDK9, thereby preventing PTEFb-mediated activation of RNA Pol II and leading to the inhibition of gene transcription of various anti-apoptotic proteins.