Atuveciclib (BAY-1143572)
Product Specifications
CAS Number
1414943-88-6
Target
CDK
Applications
Cell Cycle
Smiles
COC1=C (C=CC (=C1) F) C2=NC (=NC=N2) NC3=CC=CC (=C3) CS (=N) (=O) C
Molecular Formula
C18H18FN5O2S
Additionnal Information
Atuveciclib (BAY-1143572) is a potent and highly selective PTEFb/CDK9 inhibitor with IC50 values of 13 nM for CDK9/CycT and the ratio of IC50 values for CDK2/CDK9 is about 100. Outside the CDK family, It inhibits GSK3 kinase with IC50 values of 45 nM and 87 nM for GSK3α and GSK3β respectively.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
AMM03634G 0.05mg
Monoclonal HOXB8 Antibody (monoclonal) (M01), Clone: 4F8
Sign In for Pricing
View Details 
GTR15166353 1 Vial
Lentiviral mouse Mcm5 shRNA (UAS) - Lentiviral mouse Mcm5 shRNA (UAS, GFP) (100)
Sign In for Pricing
View Details 
bsm-54237R-BF647-01 20 µL
GABBR2 Recombinant Antibody, AbBy Fluor™ 647 Conjugated
Sign In for Pricing
View Details