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Samuraciclib (ICEC0942) hydrochloride

Product Specifications

CAS Number

1805789-54-1

Synonyms

CT7001 hydrochloride

Target

CDK

Applications

Cell Cycle

Smiles

CC (C) C1=C2N=C (C=C (N2N=C1) NCC3=CC=CC=C3) NCC4CCNCC4O.Cl

Molecular Formula

C22H31ClN6O

Additionnal Information

Samuraciclib (ICEC0942) hydrochloride is a new, orally bioavailable CDK7 inhibitor with an IC50 of 40nM. The IC50 values for CDK1, CDK2, CDK5 and CDK9 were 45-, 15-, 230- and 30-fold higher. ICEC0942 (CT7001) promotes cell cycle arrest and apoptosis.

Storage Conditions

3 years -20°C powder

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