Tolinapant (ASTX660)
Product Specifications
CAS Number
1799328-86-1
Target
IAP
Applications
Apoptosis
Smiles
CC1CN (C (CN1) CN2CCOCC2C) CC (=O) N3CC (C4=C3C=C (C (=N4) CO) CC5=CC=C (C=C5) F) (C) C
Molecular Formula
C30H42FN5O3
Additionnal Information
Tolinapant (ASTX660) is a potent, non-peptidomimetic antagonist of cIAP1/2 and XIAP that inhibits the interactions between a SMAC-derived peptide and the BIR3 domains of XIAP (BIR3-XIAP) and cIAP1 (BIR3-cIAP1) with IC50 values less than 40 and 12 nmol/L, respectively.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC883286-100 1x 100 µL
Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3286), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details ![Frataxin (FXN) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3C3]](https://cdn.genprice.uk/products/937/68dd1b6d061270361ea172b1/imageurl/ta504352bm.webp)
TA504352BM 100 µL
Frataxin (FXN) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3C3]
Sign In for Pricing
View Details 