AZD1390
Product Specifications
CAS Number
2089288-03-7
Target
ATM/ATR
Applications
PI3K/Akt/mTOR
Smiles
CC (C) N1C2=C (C=NC3=CC (=C (C=C32) C4=CN=C (C=C4) OCCCN5CCCCC5) F) N (C1=O) C
Molecular Formula
C27H32FN5O2
Additionnal Information
AZD1390 is a first-in-class orally available and CNS penetrant ATM inhibitor with an IC50 of 0.78 nM in cells and >10,000-fold selectivity over closely related members of the PIKK family of enzymes and excellent selectivity across a broad panel of kinases.
Storage Conditions
2 years -80 in solvent
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