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AZD1390

Product Specifications

CAS Number

2089288-03-7

Target

ATM/ATR

Applications

PI3K/Akt/mTOR

Smiles

CC (C) N1C2=C (C=NC3=CC (=C (C=C32) C4=CN=C (C=C4) OCCCN5CCCCC5) F) N (C1=O) C

Molecular Formula

C27H32FN5O2

Additionnal Information

AZD1390 is a first-in-class orally available and CNS penetrant ATM inhibitor with an IC50 of 0.78 nM in cells and >10,000-fold selectivity over closely related members of the PIKK family of enzymes and excellent selectivity across a broad panel of kinases.

Storage Conditions

2 years -80 in solvent

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