Cu-CPT22
Product Specifications
CAS Number
1416324-85-0
Target
TLR
Applications
Immunology & Inflammation
Smiles
CCCCCCOC (=O) C1=CC2=C (C (=C (O) C (=C2) OC) O) C (=O) C (=C1) O
Molecular Formula
C19H22O7
Additionnal Information
CU-CPT22 shows dose-dependent inhibitory effects blocking Pam3CSK4-induced TLR1/2 activation with an IC50 of 0.58 ± 0.09 μM while no significant inhibition to TLR2/6. It demonstrates minimal non-specific inhibition against a panel of 10 representative kinases (PDGFRB, MET, DDR2, SRC, MAPK1, PAK1, AKT1, PKC-γ, CAMK1, and PLK4) .
Storage Conditions
2 years -80 in solvent
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