What is the catalog number for Inavolisib (GDC-0077)?

The catalog number for Inavolisib (GDC-0077) is S8668-5mg.

What sizes are available for Inavolisib (GDC-0077)?

Inavolisib (GDC-0077) is available in the following size(s): 5 mg.

Is Inavolisib (GDC-0077) in stock?

Inavolisib (GDC-0077) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Inavolisib (GDC-0077)?

Inavolisib (GDC-0077) is manufactured by Bimake.

What is the estimated delivery time for Inavolisib (GDC-0077)?

Estimated delivery time for Inavolisib (GDC-0077) is approximately 15 business day(s), depending on your location.

Inavolisib (GDC-0077)

Product Specifications

CAS Number

2060571-02-8

Synonyms

RG6114, RO-7113755

Target

PI3K

Applications

PI3K/Akt/mTOR

Smiles

CC (C (=O) N) NC1=CC2=C (C=C1) C3=NC (=CN3CCO2) N4C (COC4=O) C (F) F

Molecular Formula

C18H19F2N5O4

Additionnal Information

Inavolisib (GDC-0077, RG6114, RO-7113755) is a potent selective inhibitor of PI3K alpha (PI3Kα) with an IC50 of 0.038 nM. GDC-0077 is >300-fold more selective for PI3K alpha over the other class I PI3K isoforms (beta, delta, and gamma) and >2000-fold more selective over PIK family members. GDC-0077 binds to the ATP binding site of PI3K and inhibits the phosphorylation of PIP2 to PIP3.