Nanvuranlat (JPH203)
Product Specifications
CAS Number
1037592-40-7
Synonyms
KYT-0353, JPH-203SBECD
Target
Amino acid transporter
Applications
Transmembrane Transporters
Smiles
C1=CC=C (C=C1) C2=NC3=CC (=CC (=C3O2) COC4=C (C=C (C=C4Cl) CC (C (=O) O) N) Cl) N
Molecular Formula
C23H19Cl2N3O4
Additionnal Information
Nanvuranlat (JPH203, KYT-0353, JPH-203SBECD), a selective L-type amino acid transporter 1 inhibitor, shows a dramatic inhibition of leucine uptake (IC50=0.06 μM) and cell growth (IC50=4.1 μM) in human colon cancer cells (HT-29), human oral cancer cells (YD-38) and leukemic cells.
Storage Conditions
2 years -80 in solvent
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