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Takinib

Product Specifications

CAS Number

1111556-37-6

Synonyms

EDHS-206

Target

TAK1

Applications

MAPK

Smiles

CCCN1C2=CC=CC=C2N=C1NC (=O) C3=CC=CC (=C3) C (=O) N

Molecular Formula

C18H18N4O2

Additionnal Information

Takinib is a potent and selective TAK1 inhibitor with an IC50 of 9.5 nM, more than 1.5 log more potent than the second and third ranked targets, IRAK4 (120 nM) and IRAK1 (390 nM), respectively. Takinib induces apoptosis.

Storage Conditions

2 years -80 in solvent

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