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IWP-O1

Product Specifications

CAS Number

2074607-48-8

Target

PORCN

Applications

Cytoskeletal Signaling

Smiles

C1=CC=C (C=C1) C2=CN=C (C=C2) NC (=O) CN3C (=C (N=N3) C4=CC=NC=C4) C5=CC=CC=C5

Molecular Formula

C26H20N6O

Additionnal Information

IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.

Storage Conditions

2 years -80 in solvent

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