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Necrostatin 2 racemate (Nec-1s)

Product Specifications

CAS Number

852391-15-2

Synonyms

7-Cl-O-Nec1, Necrostatin-1 stable, Necrostatin 1S

Target

RIP kinase

Applications

Apoptosis

Smiles

CN1C (=O) C (NC1=O) CC2=CNC3=C2C=CC=C3Cl

Molecular Formula

C13H12ClN3O2

Additionnal Information

Necrostatin 2 racemate (Nec-1s, 7-Cl-O-Nec1, Necrostatin-1 stable, Necrostatin 1S) is a stable variant of Necrostatin-1. It is a more specific RIPK1 inhibitor lacking the IDO-targeting effect, with >1000-fold more selective for RIPK1 than for any other kinase out of 485 human kinases.

Storage Conditions

2 years -80 in solvent

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