Siremadlin (HDM201)
Product Specifications
CAS Number
1448867-41-1
Synonyms
NVP-HDM201
Target
MDM2/MDMX
Applications
Apoptosis
Smiles
CC (C) N1C2=C (C (=O) N (C2C3=CC=C (C=C3) Cl) C4=CC (=CN (C4=O) C) Cl) N=C1C5=CN=C (N=C5OC) OC
Molecular Formula
C26H24Cl2N6O4
Additionnal Information
Siremadlin (HDM201) is a novel, highly potent and selective inhibitor of the p53-Mdm2 interaction with affinity constant for Mdm2 in the picomolar range and a selectivity ratio greater than 10000-fold vs Mdm4.
Storage Conditions
2 years -80 in solvent
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