What is the catalog number for VX-984?

The catalog number for VX-984 is S8593-1mg.

What sizes are available for VX-984?

VX-984 is available in the following size(s): 1 mg.

VX-984 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures VX-984?

VX-984 is manufactured by Bimake.

What is the estimated delivery time for VX-984?

Estimated delivery time for VX-984 is approximately 15 business day(s), depending on your location.

VX-984

Product Specifications

CAS Number

1476074-39-1

Synonyms

M9831

Target

DNA-PK

Applications

PI3K/Akt/mTOR

Molecular Formula

C23H21D2N7O

Additionnal Information

VX-984 (M9831) is an orally active, potent, selective, and ATP-competitive inhibitor of DNA-PK. VX-984 effectively suppresses non-homologous end joining (NHEJ) and increases DNA double-strand breaks (DSBs) . It enhances the cytotoxic effects of ionizing radiation (IR) in various cancer cell lines, including non-small cell lung cancer (NSCLC) cell lines, in vitro. Additionally, VX-984 reduces DNA-PKcs autophosphorylation.