Withaferin A (WFA)
Product Specifications
CAS Number
5119-48-2
Synonyms
WA
Target
NF-κB
Applications
NF-κB
Molecular Formula
C28H38O6
Additionnal Information
Withaferin A (WFA) potently inhibits NF-κB activation by preventing the tumor necrosis factor-induced activation of IκB kinase β via a thioalkylation-sensitive redox mechanism. Withaferin A binds to the intermediate filament (IF) protein, vimentin with antitumor and antiangiogenesis activity. Withaferin A is a steroidal lactone isolated from Withania somnifera.
Storage Conditions
3 years -20°C powder
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