Repotrectinib (TPX-0005)
Product Specifications
CAS Number
1802220-02-5
Target
Src
Applications
Protein Tyrosine Kinase
Smiles
CC1CNC (=O) C2=C3N=C (C=CN3N=C2) NC (C4=C (O1) C=CC (=C4) F) C
Molecular Formula
C18H18FN5O2
Additionnal Information
Repotrectinib (TPX-0005) is a novel ALK/ROS1/TRK inhibitor with the IC50 values of 1.01 nM for WT ALK, 1.26 nM for ALK (G1202R), and 1.08 nM for ALK (L1196M) ; also a potent SRC inhibitor (IC50 5.3 nM) .
Storage Conditions
2 years -80 in solvent
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