Serabelisib (TAK-117)
Product Specifications
CAS Number
1268454-23-4
Synonyms
INK-1117, MLN-1117
Target
PI3K
Applications
PI3K/Akt/mTOR
Smiles
C1COCCN1C (=O) C2=CN=C3N2C=C (C=C3) C4=CC5=C (C=C4) OC (=N5) N
Molecular Formula
C19H17N5O3
Additionnal Information
Serabelisib (TAK-117, INK-1117, MLN-1117) is a potent and selective oral PI3Kα isoform inhibitor (IC50 of 21 nmol/L against PI3Kα) that has demonstrated > 100-fold selectivity relative to other class I PI3K family members (PI3Kβ/γ/δ) and mTOR, and a high degree of selectivity against many other kinase.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV675211 1.0 µg DNA
KCNJ15 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 
DCC58787-01 50 mg
1-Oxa-6-azaspiro[3.3]heptane, trifluoroacetic acid
Sign In for Pricing
View Details DCC58787-02 0.5 g
1-Oxa-6-azaspiro[3.3]heptane, trifluoroacetic acid
Sign In for Pricing
View Details