PRN1371

Product Specifications

CAS Number

1802929-43-6

Target

FGFR

Applications

Protein Tyrosine Kinase

Smiles

CNC1=NC=C2C=C (C (=O) N (C2=N1) CCCN3CCN (CC3) C (=O) C=C) C4=C (C (=CC (=C4Cl) OC) OC) Cl

Molecular Formula

C26H30Cl2N6O4

Additionnal Information

PRN1371 is an irreversible covalent FGFR1-4 kinase inhibitor, with IC50s of 0.6, 1.3, 4.1, 19.3 and 8.1 nM for FGFR1, 2, 3, 4 and CSF1R, respectively.

Storage Conditions

2 years -80 in solvent

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