Tucidinostat (Chidamide)
Product Specifications
CAS Number
1616493-44-7
Synonyms
HBI-8000, CS-055
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
C1=CC (=CN=C1) C=CC (=O) NCC2=CC=C (C=C2) C (=O) NC3=C (C=C (C=C3) F) N
Molecular Formula
C22H19FN4O2
Additionnal Information
Tucidinostat (Chidamide, HBI-8000, CS-055) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.
Storage Conditions
2 years -80 in solvent
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