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Seletalisib (UCB-5857)

Product Specifications

CAS Number

1362850-20-1

Target

PI3K

Applications

PI3K/Akt/mTOR

Smiles

C1=CC2=CC (=C (N=C2C (=C1) Cl) C3=C[N+] (=CC=C3) [O-]) C (C (F) (F) F) NC4=NC=NC5=C4N=CC=C5

Molecular Formula

C23H14ClF3N6O

Additionnal Information

Seletalisib (UCB-5857) is a novel small-molecule inhibitor of PI3Kδ with an IC50 value of 12 nM and shows significant selectivity to PI3Kδ with respect to the other class I PI3K isoforms (between 24- and 303-fold) .

Storage Conditions

3 years -20°C powder

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