What is the catalog number for Avapritinib?

The catalog number for Avapritinib is S8553-5mg.

What sizes are available for Avapritinib?

Avapritinib is available in the following size(s): 5 mg.

Is Avapritinib in stock?

Avapritinib is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Avapritinib?

Avapritinib is requires dry ice shipping.

Who manufactures Avapritinib?

Avapritinib is manufactured by Bimake.

What is the estimated delivery time for Avapritinib?

Estimated delivery time for Avapritinib is approximately 15 business day(s), depending on your location.

Avapritinib

Product Specifications

CAS Number

1703793-34-3

Synonyms

BLU-285

Target

PDGFR

Applications

Protein Tyrosine Kinase

Smiles

CC (C1=CC=C (C=C1) F) (C2=CN=C (N=C2) N3CCN (CC3) C4=NC=NN5C4=CC (=C5) C6=CN (N=C6) C) N

Molecular Formula

C26H27FN10

Additionnal Information

Avapritinib is a small molecule kinase inhibitor that potently inhibits PDGFRα D842V mutant activity in vitro (IC50 = 0.5 nM) and PDGFRα D842V autophosphorylation in the cellular setting (IC50 = 30 nM) ; also a potent inhibitor of the analogous Kit (c-Kit) mutation, D816V in Kit (c-Kit) Exon 17 (IC50 = 0.5 nM) .