Alrizomadlin
Product Specifications
CAS Number
1818393-16-6
Synonyms
APG-115, AA-115
Target
MDM2/MDMX
Applications
Apoptosis
Molecular Formula
C34H38Cl2FN3O4
Additionnal Information
Alrizomadlin (APG-115, AA-115) is a highly potent and efficacious inhibitor of MDM2 and binds to MDM2 with IC50 of 3.8 nM. It exhibits potent antiproliferative and apoptogenic activities and also significantly reduces tumor burden and prolonged survival in AML xenograft models.
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