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ARN-3236

Product Specifications

CAS Number

1613710-01-2

Target

SIK

Applications

Immunology & Inflammation

Smiles

COC1=CC (=C (C=C1) C2=CNC3=NC=CC (=C23) C4=CSC=C4) OC

Molecular Formula

C19H16N2O2S

Additionnal Information

ARN-3236 is a potent, orally available and selective inhibitor of salt-inducible kinase 2 (SIK2) with IC50 of <1 nM, 21.63 nM and 6.63 nM for SIK2, SIK1 and SIK3, respectively. ARN-3236 induces apoptosis in cancer cells.

Storage Conditions

3 years -20°C powder

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