FM-381
Product Specifications
CAS Number
2226521-65-7
Target
JAK
Applications
Angiogenesis
Smiles
CN (C) C (=O) C (=CC1=CC=C (O1) C2=NC3=CN=C4C (=C3N2C5CCCCC5) C=CN4) C#N
Molecular Formula
C24H24N6O2
Additionnal Information
FM-381 is a JAK3 specific reversible covalent inhibitor with IC50 of 127 pM for JAK3 and demonstrates 400-, 2,700- and 3,600-fold selectivity over JAK1, JAK2, and TYK2, respectively.
Storage Conditions
2 years -80 in solvent
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