Temuterkib (LY3214996)
Product Specifications
CAS Number
1951483-29-6
Target
ERK
Applications
MAPK
Smiles
CC1 (C2=C (C=C (S2) C3=NC (=NC=C3) NC4=CC=NN4C) C (=O) N1CCN5CCOCC5) C
Molecular Formula
C22H27N7O2S
Additionnal Information
Temuterkib (LY3214996) is a selective and novel ERK1/2 inhibitor with IC50 of 5 nM for both enzymes in biochemical assays. It potently inhibits cellular phospho-RSK1 in BRAF and RAS mutant cancer cell lines.
Storage Conditions
2 years -80 in solvent
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