AD80
Product Specifications
CAS Number
1384071-99-1
Target
C-RET
Applications
Protein Tyrosine Kinase
Smiles
CC (C) N1C2=NC=NC (=C2C (=N1) C3=CC=C (C=C3) NC (=O) NC4=C (C=CC (=C4) C (F) (F) F) F) N
Molecular Formula
C22H19F4N7O
Additionnal Information
AD80, a multikinase inhibitor, shows strong activity against human RET (c-RET), BRAF, S6K, and SRC but were much less active than either AD57 or AD58 against mTOR. The IC50 value for RET is 4 nM.
Storage Conditions
2 years -80 in solvent
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