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KRpep-2d

Product Specifications

CAS Number

2098181-84-9

Target

Ras

Applications

Apoptosis

Smiles

CCC (C) C1NC (=O) C (CC2=CC=C (O) C=C2) NC (=O) C (CC (C) C) NC (=O) C3CCCN3C (=O) C (CSSCC (NC (=O) C (NC (=O) C4CCCN4C (=O) C (CC (O) =O) NC (=O) C (CC5=CC=C (O) C=C5) NC (=O) C (CO) NC1=O) C (C) C) C (=O) NC (CCCNC (N) =N) C (=O) NC (CCCNC (N) =N) C (=O) N

Molecular Formula

C108H182N44O25S2

Additionnal Information

KRpep-2d is a K-Ras (G12D) selective inhibitory cyclic peptide with selectivity against wild-type (WT) K-Ras and the K-Ras (G12C) mutant. The IC50 value is 1.6 nM.

Storage Conditions

2 years -80 in solvent

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