What is the catalog number for EED226?

The catalog number for EED226 is S8496-5mg.

What sizes are available for EED226?

EED226 is available in the following size(s): 5 mg.

EED226 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for EED226?

EED226 is requires dry ice shipping.

Who manufactures EED226?

EED226 is manufactured by Bimake.

What is the estimated delivery time for EED226?

Estimated delivery time for EED226 is approximately 15 business day(s), depending on your location.

EED226

Product Specifications

CAS Number

2083627-02-3

Target

Epigenetic Reader Domain

Applications

Epigenetics

Smiles

CS (=O) (=O) C1=CC=C (C=C1) C2=CN=C (N3C2=NN=C3) NCC4=CC=CO4

Molecular Formula

C17H15N5O3S

Additionnal Information

EED226 is a potent, selective, and orally bioavailable a novel allosteric Polycomb repressive complex 2 (PRC2) inhibitor with an IC50 of 23.4 nM when the H3K27me0 peptide was used as substrate and an IC50 of 53.5 nM when the mononucleosome was used as the substrate. It directly binds to the H3K27me3 binding pocket of EED.