GSK'872
Product Specifications
CAS Number
1346546-69-7
Synonyms
GSK2399872A
Target
RIP kinase
Applications
Apoptosis
Smiles
CC (C) S (=O) (=O) C1=CC2=C (C=CN=C2C=C1) NC3=CC4=C (C=C3) SC=N4
Molecular Formula
C19H17N3O2S2
Additionnal Information
GSK'872 is a potent and selective RIP3 kinase inhibitor which binds RIP3 kinase domain with high affinity (IC50=1.8 nM) and inhibits kinase activity with IC50 of 1.3 nM. It has minimal cross-reactivity.
Storage Conditions
2 years -80 in solvent
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